These are two injuries that will limit Newton even if he is able to play in the season opener. The ankle injury will slow him down and limit his mobility, and anytime he takes a hit, he'll feel it in his ribs.
Offensive coordinator Mike Shula could keep designed QB runs to a minimum early on in the season to help keep Newton healthy. DeAngelo Williams, Jonathan Stewart and Mike Tolbert could see some extra carries in the first few weeks.
If Newton can't go in week 1, backup Derek Anderson would get the start.