The Super Bowl is played at a neutral site so that neither team playing in the game will have any type of advantage. However I think Seattle does have the advantage playing in Arizona. Yes, of course Seattle has the biggest home field advantage in the NFL, playing in front of the 12th man but Russell Wilson is the x-factor in this Super Bowl and numbers don't lie.
Russell Wilson had a very good year, completing 63.1% of his passes for 3,475 yards and 20 touchdowns with just 7 interceptions. His passer rating was 95.0 on the year, but if it wasn't for his road games, his passer rating would be much lower.
In 8 home games this year, Wilson posted a 80.8 passer rating. He threw just 6 touchdowns while being picked off 6 times and only completed 61% of his passes. Even his rushing numbers weren't great. On 61 carries Wilson ran for 326 yards (5.3 avg) and 2 touchdowns.
On the road this year, Wilson posted a passer rating of 107.6. He completed 65% of his passes and threw for 14 touchdowns and just 1 interception. On the ground, he ran 57 times for 523 yards (9.2 avg) and 4 touchdowns.
Tom Brady on the other hand is the exact opposite. He's amazing playing in Foxboro, as he threw for 19 touchdowns and just 3 interceptions. His passer rating at home was 103.8. On the road he threw for 14 touchdowns and 6 interceptions. His passer rating on the road was 90.4.
Even the sacks were on two different levels. At home Brady was sacked just 6 times, but he was sacked 15 times on the road.